Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Skeletal muscle sarcoplasmic reticulum phenotype in myotonic dystrophy.

Neuromuscular disorders : NMD - 1 Jan 1996

Damiani E, Angelini C, Pelosi M, Sacchetto R, Bortoloso E, Margreth A

Abstract excerpt

In this study we investigated the sarcoplasmic reticulum (SR), alongside myofibrillar phenotype, in muscle samples from five Myotonic Dystrophy (DM) patients and five control individuals. DM muscles exhibited as a common feature, a decrease in the slow isoform of myosin heavy chain (MHC) and of troponin C in myofibrils. We observed a match between myofibrillar changes and changes in SR membrane markers specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged
Share to Blotting, Western

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to Electrophoresis, Polyacrylamide Gel

Share to Muscle Proteins

Share to Muscle, Skeletal

Source

Identifiers

PMID: 8845717
DOI: 10.1016/0960-8966(95)00016-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Skeletal muscle sarcoplasmic reticulum phenotype in myotonic dystrophy.PMID 8845717Read ↗

Alternative splicing alterations of Ca 2+ handling genes are associated with Ca 2+ signal dysregulation in myotonic dystrophy type 1 ( DM 1) and type 2 ( DM 2) myotubesSemantic proximity Read ↗

Ca2+ handling abnormalities in early-onset muscle diseases: Novel concepts and perspectives.Semantic proximity Read ↗

Ca2+ signalling and muscle disease.Semantic proximity Read ↗

Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1.Semantic proximity Read ↗

Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum.Semantic proximity Read ↗

Histopathology of Duchenne muscular dystrophy in correlation with changes in proteomic biomarkers.Semantic proximity Read ↗

A Calsequestrin-1 Mutation Associated with a Skeletal Muscle Disease Alters Sarcoplasmic Ca2+ Release.Semantic proximity Read ↗

Increased sarcolipin expression and decreased sarco(endo)plasmic reticulum Ca2+ uptake in skeletal muscles of mouse models of Duchenne muscular dystrophySemantic proximity Read ↗

Pathogenic TNNT1 variants are associated with aberrant thin filament compliance and myofibre hyper-contractility.Semantic proximity Read ↗

Disrupted Calcium Homeostasis in Duchenne Muscular Dystrophy: A Common Mechanism behind Diverse ConsequencesSemantic proximity Read ↗

RyR1 protein content is reduced in inflammatory and mitochondrial myopathies and induces ER stressSemantic proximity Read ↗

Abnormal distribution of calcium-handling proteins: a novel distinctive marker in core myopathies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.