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Article

Human leukocyte antigen B*0702 is protective against ocular Stevens-Johnson syndrome/toxic epidermal necrolysis in the UK population.

Scientific reports - 3 Feb 2021

Butt Gibran F, Hassan Ali, Wallace Graham R, Kinoshita Shigeru, Ahmad Sajjad, Ueta Mayumi, Rauz Saaeha

Abstract excerpt

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis (SJS/TEN) are part of a disease continuum of vesiculobullous mucocutaneous reactions affecting the skin and mucous membranes including the ocular surface. Manifestations of disease range from mild dry eye to progressive conjunctival cicatrisation, limbal epithelial stem cell failure and corneal blindness. In Far Eastern and South East Asian populations where...

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Identifiers

PMID: 33536518
DOI: 10.1038/s41598-021-82400-3
PMCID: PMC7859395

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Source receipt: pubmed, retrieved 7 Sept 2026.

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