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Article

Genetic analysis of schizophrenia as an example of a putative multifactorial trait.

Annals of human genetics - 1 Mar 1996

Pritchard D J

Abstract excerpt

A new method for analysis of multifactorial traits is described which involves mathematical definition of MZ and DZ twin concordances in terms of penetrance and the number of contributory genes. This allows the number of major genes and their joint penetrance to be estimated. Application to familial schizophrenia indicates causation by a single dominant allele, a deduction supported by several treatments of...

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Identifiers

PMID: 8839126
DOI: 10.1111/j.1469-1809.1996.tb01182.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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