Article
Antigen-presenting cells in the skin and placenta in pemphigoid gestationis.
The British journal of dermatology - 1 May 1990
Kelly S E, Black M M, Fleming S
Abstract excerpt
In pemphigoid gestationis (PG), one of the major initiating events is the aberrant expression of the class II molecules of the major histocompatibility complex in the placenta. We used a panel of 13 monoclonal antibodies to investigate the phenotype of the MHC class II positive antigen-presenting cells (APC) in the skin and placenta in PG. In the skin, the APC show reactivity with a variety of macrophage markers...
Topics
- Antigen-Presenting Cells
- Female
- Histocompatibility Antigens Class II
- Humans
- Immunohistochemistry
- Pemphigoid, Bullous
- Phenotype
- Placenta
- Pregnancy
- Pregnancy Complications
- Skin