Article
An association study of a neurotrophin-3 (NT-3) gene polymorphism with schizophrenia.
Acta psychiatrica Scandinavica - 1 Dec 1995
Dawson E, Powell J F, Sham P C, Nöthen M, Crocq M A, Propping P, Körner J, Rietschel M, van Os J, Wright P
Abstract excerpt
Since abnormalities of brain development play a role in the aetiology of schizophrenia, growth factors, known to play a role in neurodevelopment, such as neurotrophin-3 (NT-3), are therefore candidate genes for this disorder. The A3/147 bp allele of a dinucleotide repeat polymorphism in the promoter region of the NT-3 gene has been reported as occurring more frequently in a sample of Japanese schizophrenics...
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