Article
Neurotrophin-3 gene polymorphism associated with schizophrenia.
Acta psychiatrica Scandinavica - 1 Jun 1994
Nanko S, Hattori M, Kuwata S, Sasaki T, Fukuda R, Dai X Y, Yamaguchi K, Shibata Y, Kazamatsuri H
Abstract excerpt
The recent possible neurodevelopmental etiology of schizophrenia makes the neurotrophin-3 (NT-3) gene an interesting candidate locus. We studied the allelic distributions of dinucleotide repeat polymorphism at the NT-3 gene locus in 70 patients with schizophrenia and in 70 controls. A highly significant difference between the two groups was observed at the allele A3. Even Bonferroni's correction was used, the...
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