Article
Erythromycin production in Saccharopolyspora erythraea does not require a functional propionyl-CoA carboxylase.
Molecular microbiology - 1 Mar 1996
Donadio S, Staver M J, Katz L
Abstract excerpt
Using an oligonucleotide corresponding to the consensus sequence for the biotin-binding motif, two unlinked genetic loci, bpl1 and bpl2, were cloned from the erythromycin producer Saccharopolyspora erythraea and the nucleotide sequences of a c. 4 kb segment from each determined. The two loci share a virtually identical segment of 1746 nucleotides, coinciding with most of the genes designated bcpA1 and bcpA2...
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