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Article

Genes involved in cell cycle G1 checkpoint control are frequently mutated in human melanoma metastases.

British journal of cancer - 1 Sept 1996

Platz A, Sevigny P, Norberg T, Ring P, Lagerlöf B, Ringborg U

Abstract excerpt

A common characteristic of cancer cells is unrestrained cell division. This may be caused by mutational changes in genes coding for components of cell cycle-controlling networks. Alterations in genes involved in G1 checkpoint control have been registered in many human tumours, and investigations from several laboratories show that such alterations, taken together, are the most frequent changes detected in cancer...

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Share to Carrier Proteins
Share to Cell Cycle Proteins
Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

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Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Source

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Identifiers

PMID: 8826861
DOI: 10.1038/bjc.1996.460
PMCID: PMC2074743

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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