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Article

Fragile X founder chromosomes in Italy: a few initial events and possible explanation for their heterogeneity.

American journal of medical genetics - 12 Jul 1996

Chiurazzi P, Genuardi M, Kozak L, Giovannucci-Uzielli M L, Bussani C, Dagna-Bricarelli F, Grasso M, Perroni L, Sebastio G, Sperandeo M P, Oostra B A, Neri G

Abstract excerpt

A total of 137 fragile X and 235 control chromosomes from various regions of Italy were haplotyped by analyzing two neighbouring marker microsatellites, FRAXAC1 and DXS548. The number of CGG repeats at the 5' end of the FMR1 gene was also assessed in 141 control chromosomes and correlated with their haplotypes. Significant linkage disequilibrium between some "major" haplotypes and fragile X was observed, while...

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Source

Identifiers

PMID: 8826478
DOI: 10.1002/(SICI)1096-8628(19960712)64:1<209::AID-AJMG38>3.0.CO;2-P

Genes

FMR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Fragile X founder chromosomes in Italy: a few initial events and possible explanation for their heterogeneity.PMID 8826478Read ↗

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