Article
Inherited predisposition to colorectal neoplasia.
British journal of hospital medicine - 1 Jan 2000
Stephenson B M, Hall N R, Finan P J, Bishop T
Abstract excerpt
This review concentrates on the genetics of colorectal neoplasia. There is now a greater understanding of the molecular genetics of the inherited condition familial adenomatous polyposis and of the adenoma-carcinoma sequence in non-inherited colorectal cancer. We consider the evidence that sporadic colorectal cancer may also have an underlying genetic susceptibility.
Topics
- Adenomatous Polyposis Coli
- Genes, APC
- Genetic Predisposition to Disease
- Genetic Testing
- Humans
- Pedigree
- Risk Factors