Article
The effect of the stringent response on mutation rates in Escherichia coli K-12.
Molecular microbiology - 1 Jan 1996
Wright B E
Abstract excerpt
The reversion rates of two isogenic Escherichia coli K-12 auxotrophs differing only in relA have been determined in the absence or presence of serine hydroxamate, which provokes the stringent response. Reversion rates of leuB- and argH- were significantly higher in the relA+ than in the relA- strain, and the reversion rates in both strains were enhanced by serine hydroxamate. A positive correlation was...
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