Article
Stable SV40-transformation and characterisation of some DNA repair properties of fibroblasts from a trichothiodystrophy patient.
Biochimie - 1 Jan 1995
Eveno E, Quilliet X, Chevallier-Lagente O, Daya-Grosjean L, Stary A, Zeng L, Benoit A, Savini E, Ciarrocchi G, Kannouche P
Abstract excerpt
To characterize nucleotide excision repair properties of cells from trichothiodystrophy (TTD) patients genetically-related to the xeroderma pigmentosum (XP) group D, TTD skin fibroblasts from two unrelated patients (TTD1VI and TTD2VI) belonging to the TTD/XPD group were transformed with a plasmid containing SV40 large T antigen-coding sequences and some DNA repair properties, such as unscheduled DNA synthesis...
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