Article
Lymphoid involvement in a patient with acute myeloid leukemia: a direct phenotypic and genotypic study of single cells.
Genes, chromosomes & cancer - 1 Jan 1996
El-Rifai W, Larramendy M L, Ruutu T, Knuutila S
Abstract excerpt
Lymphoid involvement in acute myeloid leukemia (AML) was studied using the morphology-antibody-chromosome (MAC) combination technique in one patient. The chromosomal aberration, trisomy 8, was demonstrated in AML blasts, glycophorin A-positive erythroblasts, and CD3- and CD20/22-positive small lymphocytes. This suggests that in this patient even lymphocytes belonged to the leukemic clone.
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