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Article

Bcl-2 sensitivity differentiates two pathways for motoneuronal death in the wobbler mutant mouse.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Oct 1996

Coulpier M, Junier M P, Peschanski M, Dreyfus P A

Abstract excerpt

The molecular events leading to motoneuronal death are still poorly understood. In mammals, the bcl-2 proto-oncogene, which encodes a membrane-associated protein, has been shown to suppress both developmental motoneuronal death and experimental axotomy-induced motoneuronal death. We assessed a potential protective effect of Bcl-2 on pathological motoneuronal death processes in adult rodents. We took advantage of...

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PMID: 8815872
PMCID: PMC6579179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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