Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of a PCR-based diagnostic assay for the determination of KEL genotype in donor blood samples.

Transfusion medicine (Oxford, England) - 1 Jun 1996

Murphy M T, Fraser R H, Goddard J P

Abstract excerpt

The polymorphism which determines expression of Kell and Cellano antigens on the redcell surface has been reported to be a single C-->T nucleotide substitution at residue 701 where T codes for the presence of Kell antigen. This was confirmed by the direct automated sequencing of PCR products amplified from individuals of known Kell phenotype. The substitution creates a Bsm I restriction enzyme site and this has...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Donors
Share to Erythrocytes
Share to Genome, Human

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Isoantigens

Share to Phenotype

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 8809961
DOI: 10.1046/j.1365-3148.1996.d01-62.x

Genes

KEL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of a PCR-based diagnostic assay for the determination of KEL genotype in donor blood samples.PMID 8809961Read ↗

Molecular basis of the Kell (K1) phenotype.Semantic proximity Read ↗

KEL*02 alleles with alterations in and around exon 8 in individuals with apparent KEL:1,-2 phenotypes.Semantic proximity Read ↗

Prenatal diagnosis of Kell blood group genotypes: KEL1 and KEL2.Semantic proximity Read ↗

Genotyping of KEL1 and KEL2 of the human Kell blood group system by the polymerase chain reaction with sequence-specific primers.Semantic proximity Read ↗

Three novel alleles in the Kell blood group system resulting in the Knull phenotype and the first in a Native American.Semantic proximity Read ↗

A KEL gene encoding serine at position 193 of the Kell glycoprotein results in expression of KEL1 antigen.Semantic proximity Read ↗

Point mutations in KEL exon 8 determine a high-incidence (RAZ) and a low-incidence (KEL25, VLAN) antigen of the Kell blood group system.Semantic proximity Read ↗

Novel KEL allele associated with loss of Kpb identified in a white blood donor.Semantic proximity Read ↗

Molecular basis of Kell blood group phenotypes.Semantic proximity Read ↗

Molecular basis of two novel and related high-prevalence antigens in the Kell blood group system, KUCI and KANT, and their serologic and spatial association with K11 and KETI.Semantic proximity Read ↗

An innovative test for non-invasive Kell genotyping on circulating fetal DNA by means of the allelic discrimination of K1 and K2 antigens.Semantic proximity Read ↗

Silent KEL alleles identified from Japanese individuals with the Ko phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.