Effects of lead on growth plate chondrocyte phenotype.

doi:10.1006/taap.1996.0209

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Article

Effects of lead on growth plate chondrocyte phenotype.

Toxicology and applied pharmacology - 1 Sept 1996

Hicks D G, O'Keefe R J, Reynolds K J, Cory-Slechta D A, Puzas J E, Judkins A, Rosier R N

Abstract excerpt

Lead toxicity is a major public health problem in the United States. The skeleton serves as the major reservoir for ingested lead, where it is incorporated into bone matrix during calcification. While lead in bone has been considered inactive, mounting clinical and epidemiological data has shown...

Topics

Animals
Cell Division
Cell Survival
Cells, Cultured
Chickens
Collagen
Growth Plate
In Situ Hybridization
Lead
Phenotype
Proteoglycans
Thymidine

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