Article
Effects of lead on growth plate chondrocyte phenotype.
Toxicology and applied pharmacology - 1 Sept 1996
Hicks D G, O'Keefe R J, Reynolds K J, Cory-Slechta D A, Puzas J E, Judkins A, Rosier R N
Abstract excerpt
Lead toxicity is a major public health problem in the United States. The skeleton serves as the major reservoir for ingested lead, where it is incorporated into bone matrix during calcification. While lead in bone has been considered inactive, mounting clinical and epidemiological data has shown a strong correlation between lead exposure and adverse effects on stature in children. These epidemiologic data suggest...
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