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Article

Reduced growth cone motility in cultured neurons from Drosophila memory mutants with a defective cAMP cascade.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Sept 1996

Kim Y T, Wu C F

Abstract excerpt

Drosophila memory mutants dunce (dnc) and rutabaga (rut) are known to have altered intracellular cAMP levels, nerve terminal growth, and plasticity of synaptic transmission. Because the growth cone is responsible for neurite outgrowth and synaptogenesis, video microscopy was used to examine growth cone morphology and behavior of mutant neurons in larval CNS cultures. We found that growth cone exploratory movement...

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PMID: 8795615
PMCID: PMC6578966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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