Reduced growth cone motility in cultured neurons from Drosophila memory mutants with a defective cAMP cascade.

Article

Reduced growth cone motility in cultured neurons from Drosophila memory mutants with a defective cAMP cascade.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Sept 1996

Kim Y T, Wu C F

Abstract excerpt

Drosophila memory mutants dunce (dnc) and rutabaga (rut) are known to have altered intracellular cAMP levels, nerve terminal growth, and plasticity of synaptic transmission. Because the growth cone is responsible for neurite outgrowth and synaptogenesis, video microscopy was used to examine growt...

Topics

Animals
Bucladesine
Cells, Cultured
Central Nervous System
Colforsin
Cyclic AMP
Drosophila melanogaster
Larva
Memory
Mutation
Neurites
Neurons

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