Article
Melanosomal tyrosine transport in normal and pink-eyed dilution murine melanocytes.
Pigment cell research - 1 Oct 1995
Gahl W A, Potterf B, Durham-Pierre D, Brilliant M H, Hearing V J
Abstract excerpt
Tyrosine is the endogenous substrate for melanin production within melanosomes, but the method of tyrosine transport into the melanosome has not been investigated. In the mouse, melanogenesis is disrupted by mutations in the p gene resulting in the pink-eyed dilution phenotype; it has been suggested that the p gene codes for a tyrosine transport protein. We determined that normal (melan-a) melanosome-rich...
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