Article
Systematic search of susceptibility loci with methods using gametic disequilibrium.
Genetic epidemiology - 1 Jan 1995
Bickeböller H, Margaritte-Jeannin P, Babron M C, Clerget-Darpoux F
Abstract excerpt
Susceptibility genes are identified for a simulated complex trait by a systematic genome search for linkage between disease and a genetic marker in the presence of gametic disequilibrium. The transmission/disequilibrium tests TDTa or TDTg for multiallelic markers compare transmitted and nontransmitted alleles or the genotypes formed by the two transmitted alleles and the genotypes formed by the two nontransmitted...
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