Article
Monoclonal origin of multicentric Kaposi's sarcoma lesions.
The New England journal of medicine - 3 Apr 1997
Rabkin C S, Janz S, Lash A, Coleman A E, Musaba E, Liotta L, Biggar R J, Zhuang Z
Abstract excerpt
BACKGROUND: Kaposi's sarcoma has features of both hyperplastic proliferation and neoplastic growth. Multiple lesions, in which spindle cells are prominent, often arise synchronously over widely dispersed areas. We tested the hypothesis that the spindle cells in these multicentric lesions originate from a single clone of precursor cells. METHODS: To determine whether Kaposi's sarcoma is a monoclonal disorder, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
