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Article

Growth hormone insensitivity syndrome (Laron syndrome): main characteristics and effects of IGF1 treatment.

Diabetes & metabolism - 1 Jul 1996

Carel J C, Chaussain J L, Chatelain P, Savage M O

Abstract excerpt

Growth hormone (GH) insensitivity is a pathological state characterized by a disturbance of the physiological relationship between GH secretion, synthesis of insulin-like growth-factor I (IGF-1) and the biological actions of GH. Laron syndrome, the prototype for GH insensitivity, is most often due to GH receptor deficiency. However, this syndrome is heterogeneous in terms of growth characteristics, bio-chemical...

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Identifiers

PMID: 8767171

Genes

IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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