Article
Growth hormone insensitivity syndrome (Laron syndrome): main characteristics and effects of IGF1 treatment.
Diabetes & metabolism - 1 Jul 1996
Carel J C, Chaussain J L, Chatelain P, Savage M O
Abstract excerpt
Growth hormone (GH) insensitivity is a pathological state characterized by a disturbance of the physiological relationship between GH secretion, synthesis of insulin-like growth-factor I (IGF-1) and the biological actions of GH. Laron syndrome, the prototype for GH insensitivity, is most often du...
Topics
- Genetic Heterogeneity
- Growth Hormone
- Humans
- Insulin-Like Growth Factor I
- Phenotype
- Receptors, Somatotropin
- Syndrome