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Article

Human fetal enterocytes in vitro: modulation of the phenotype by extracellular matrix.

Proceedings of the National Academy of Sciences of the United States of America - 23 Jul 1996

Sanderson I R, Ezzell R M, Kedinger M, Erlanger M, Xu Z X, Pringault E, Leon-Robine S, Louvard D, Walker W A

Abstract excerpt

The differentiation of small intestinal epithelial cells may require stimulation by microenvironmental factors in vivo. In this study, the effects of mesenchymal and luminal elements in nonmalignant epithelia] cells isolated from the human fetus were studied in vitro. Enterocytes from the human fetus were cultured and microenvironmental factors were added in stages, each stage more closely approximating the...

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Identifiers

PMID: 8755542
DOI: 10.1073/pnas.93.15.7717
PMCID: PMC38813

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