Genotyping of a patient homozygous for a rare apolipoprotein E1 [Gly127-->Asp; Arg158-->Cys] (Weisgraber allele).

doi:10.1007/BF02436763

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Article

Genotyping of a patient homozygous for a rare apolipoprotein E1 [Gly127-->Asp; Arg158-->Cys] (Weisgraber allele).

Journal of inherited metabolic disease - 1 Jan 1995

Iron A, Richard P, de Zulueta M P, Thomas G, Thomas M

Abstract excerpt

We examined the apolipoprotein E polymorphism of an obese patient presenting non-insulin-dependent diabetes, hypertension and moderate lipid disturbances. The apolipoprotein E genotyping carried out from leukocyte DNA using PCR amplification and restriction enzyme digestion demonstrated homozygos...

Topics

Alleles
Apolipoproteins E
Base Sequence
Female
Genotype
Homozygote
Humans
Middle Aged
Molecular Sequence Data
Mutation

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