Article
Response to therapy of a type III hyperlipoproteinemic subject with the rare apolipoprotein E1 (Gly127----Asp, Arg158----Cys) variant.
The Clinical investigator - 1 Jul 1992
Feussner G, Ziegler R
Abstract excerpt
In a preceding paper, we described the molecular biological defects in a patient with a severe form of the familial lipoprotein disorder type III hyperlipoproteinemia (HLP) and an unusual apolipoprotein (apo) E1 phenotype and epsilon 1/"null" genotype. The index case was a 60-year-old white male of German ancestry who suffered from a myocardial infarction at age 50 years. He had distinctly elevated levels of...
Topics
- Alleles
- Apolipoproteins E
- Bezafibrate
- Cholesterol, Dietary
- Combined Modality Therapy
- Dietary Fats
- Genotype
- Humans
- Hyperlipoproteinemia Type III
- Male
- Middle Aged
