Article
Identification of a new apolipoprotein E variant (E2 Arg142-->Leu) in type III hyperlipidemia.
Atherosclerosis - 6 Jan 1995
Richard P, de Zulueta M P, Beucler I, De Gennes J L, Cassaigne A, Iron A
Abstract excerpt
A new rare apolipoprotein E mutant was identified as we were investigating the apolipoprotein E genotype of patients with type III hyperlipidemia (HLP III). The unusual DNA restriction fragment length polymorphism profile and then the sequence analysis of a PCR amplified fragment of the proband's...
Topics
- Aged
- Amino Acid Sequence
- Apolipoproteins E
- Clofibric Acid
- Fibric Acids
- Genotype
- Humans
- Hyperlipoproteinemia Type III
- Hypolipidemic Agents
- Male
- Middle Aged
- Molecular Sequence Data
- Phenotype
- Polymorphism, Restriction Fragment Length
- Sequence Analysis, DNA