Article
A novel polymorphism of apolipoprotein A-IV is the result of an asparagine to serine substitution at residue 127.
Biochimica et biophysica acta - 16 Jan 1992
Tenkanen H, Koskinen P, Metso J, Baumann M, Lukka M, Kauppinen-Mäkelin R, Kontula K, Taskinen M R, Mänttäri M, Manninen V
Abstract excerpt
We have identified a hitherto unknown genetic polymorphism of apolipoprotein A-IV (apoA-IV). The molecular basis for this polymorphism is an A to G substitution at nucleotide 1687 resulting in an Asn to Ser change of amino acid 127. The frequencies of the two apoA-IV alleles (designated apoA-IV127Asn and apoA-IV127Ser), determined by Hin c II restriction analysis of PCR amplified exon three of the apoA-IV gene,...
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