A novel polymorphism of apolipoprotein A-IV is the result of an asparagine to serine substitution at residue 127.

doi:10.1016/0925-4439(92)90147-f

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Article

A novel polymorphism of apolipoprotein A-IV is the result of an asparagine to serine substitution at residue 127.

Biochimica et biophysica acta - 16 Jan 1992

Tenkanen H, Koskinen P, Metso J, Baumann M, Lukka M, Kauppinen-Mäkelin R, Kontula K, Taskinen M R, Mänttäri M, Manninen V

Abstract excerpt

We have identified a hitherto unknown genetic polymorphism of apolipoprotein A-IV (apoA-IV). The molecular basis for this polymorphism is an A to G substitution at nucleotide 1687 resulting in an Asn to Ser change of amino acid 127. The frequencies of the two apoA-IV alleles (designated apoA-IV12...

Topics

Alleles
Amino Acid Sequence
Apolipoproteins A
Asparagine
Base Sequence
Cholesterol
Codon
Genotype
Humans
Hyperlipidemias
Lipoproteins
Male
Molecular Sequence Data
Myocardial Infarction
Polymorphism, Genetic
Serine
Threonine
Triglycerides

Source

Open in PubMed

Identifiers

PMID: 1737067
DOI: 10.1016/0925-4439(92)90147-f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1737067-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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