Article
The amino-terminal part of ActA is critical for the actin-based motility of Listeria monocytogenes; the central proline-rich region acts as a stimulator.
Molecular microbiology - 1 Nov 1995
Lasa I, David V, Gouin E, Marchand J B, Cossart P
Abstract excerpt
The intracellular bacterial pathogen Listeria monocytogenes moves inside the host-cell cytoplasm propelled by continuous actin assembly at one pole of the bacterium. This process requires expression of the bacterial surface protein ActA. Recently, in order to identify the regions of ActA which ar...
Topics
- Actins
- Animals
- Bacterial Proteins
- Base Sequence
- Blotting, Western
- Cell Movement
- Gene Expression Regulation, Bacterial
- Listeria monocytogenes
- Membrane Proteins
- Microscopy, Fluorescence
- Molecular Sequence Data
- Mutation
- Phosphoric Monoester Hydrolases
- Sequence Alignment
- Xenopus laevis