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Article

Three regions within ActA promote Arp2/3 complex-mediated actin nucleation and Listeria monocytogenes motility.

The Journal of cell biology - 7 Aug 2000

Skoble J, Portnoy D A, Welch M D

Abstract excerpt

The Listeria monocytogenes ActA protein induces actin-based motility by enhancing the actin nucleating activity of the host Arp2/3 complex. Using systematic truncation analysis, we identified a 136-residue NH(2)-terminal fragment that was fully active in stimulating nucleation in vitro. Further deletion analysis demonstrated that this fragment contains three regions, which are important for nucleation and share...

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Identifiers

PMID: 10931865
DOI: 10.1083/jcb.150.3.527
PMCID: PMC2175181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Three regions within ActA promote Arp2/3 complex-mediated actin nucleation and Listeria monocytogenes motility.PMID 10931865Read ↗

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