C-JUN/AP-1 as possible mediators of tumor necrosis factor-alpha-induced apoptotic response in mouse JB6 tumor cells.

Article

C-JUN/AP-1 as possible mediators of tumor necrosis factor-alpha-induced apoptotic response in mouse JB6 tumor cells.

Oncology research - 1 Jan 1995

Singh N, Sun Y, Nakamura K, Smith M R, Colburn N H

Abstract excerpt

Sensitivity to cell killing by tumor necrosis factor (TNF)-alpha was seen in the JB6-derived transformed mouse RT101 cell variants previously described as resistant to 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced killing, while the TPA-sensitive variants were resistant to killing by TNF-alp...

Topics

Animals
Antioxidants
Apoptosis
Cell Division
Cell Line, Transformed
Chromatin
Genetic Variation
Growth Inhibitors
Mice
Proto-Oncogene Proteins c-jun
Time Factors
Transcription Factor AP-1
Tumor Necrosis Factor-alpha

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