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Rapid detection of glucose-6-phosphate dehydrogenase gene mutations by denaturing high-performance liquid chromatography.

Clinical biochemistry - 1 Nov 2005

Tseng Ching-Ping, Huang Chien-Ling, Chong Kowit-Yu, Hung Iou-Jih, Chiu Daniel Tsun-Yee

Abstract excerpt

OBJECTIVES: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common inherited disorder worldwide. Different kinds of G6PD mutations may result in variable severity of clinical onset in G6PD-deficient individuals. In this study, a reliable molecular diagnostic method was developed for rapid detection of G6PD gene mutation. DESIGN AND METHODS: Primers were designed to amplify G6PD gene fragments that were...

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PMID: 16137669
DOI: 10.1016/j.clinbiochem.2005.07.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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