Article
Interclonal variations in the molecular karyotype of Trypanosoma cruzi: chromosome rearrangements in a single cell-derived clone of the G strain.
PloS one - 1 Jan 2013
Lima Fabio Mitsuo, Souza Renata Torres, Santori Fábio Rinaldo, Santos Michele Fernandes, Cortez Danielle Rodrigues, Barros Roberto Moraes, Cano Maria Isabel, Valadares Helder Magno Silva, Macedo Andréa Mara, Mortara Renato Arruda, da Silveira José Franco
Abstract excerpt
Trypanosoma cruzi comprises a pool of populations which are genetically diverse in terms of DNA content, growth and infectivity. Inter- and intra-strain karyotype heterogeneities have been reported, suggesting that chromosomal rearrangements occurred during the evolution of this parasite. Clone D11 is a single-cell-derived clone of the T. cruzi G strain selected by the minimal dilution method and by infecting...
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