Arylsulfatase A: relationship of genotype to variant electrophoretic properties.

doi:10.1007/BF02396247

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Article

Arylsulfatase A: relationship of genotype to variant electrophoretic properties.

Biochemical genetics - 1 Apr 1996

Park D S, Poretz R D, Ricketts M H, Manowitz P

Abstract excerpt

Previous work has shown that specific electrophoretic variants of arylsulfatase A occur more frequently among alcoholic patients than among psychiatric and normal controls. The present study sequenced the gene for two of these electrophoretic variants, IIIa and IIIb. Both contain an A-to-G transi...

Topics

Alcoholism
Alleles
Base Sequence
Blood Platelets
Cerebroside-Sulfatase
DNA Primers
Electrophoresis, Polyacrylamide Gel
Genetic Variation
Genotype
Heterozygote
Humans
Molecular Sequence Data
Phenotype
Point Mutation
Polymerase Chain Reaction

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