Article
[The androgen receptor: molecular pathology].
Journal de la Societe de biologie - 1 Jan 2002
Sultan Ch, Gobinet J, Terouanne B, Paris F, Belon Ch, Jalaguier S, Georget V, Poujol N, Auzou G, Lumbroso S
Abstract excerpt
Androgens play a crucial role in the development, maintenance and regulation of male phenotype and reproductive physiology through the androgen receptor, a transcription factor. Testosterone or dihydrotestosterone binding induces a trans-conformation of the androgen receptor and allows its translocation into the nucleus, where it recognizes specific DNA sequences. Recent developments in molecular genetics, as...
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