Article
Mutation segregation and rapid carrier detection of X-linked muscular dystrophy in dogs.
American journal of veterinary research - 1 May 1996
Bartlett R J, Winand N J, Secore S L, Singer J T, Fletcher S, Wilton S, Bogan D J, Metcalf-Bogan J R, Bartlett W T, Howell J M, Cooper B J, Kornegay J N
Abstract excerpt
OBJECTIVES: To use exon 7-specific genomic polymerase chain reaction (PCR) products to identify the genotypes of normal, affected, and carrier female dogs in pedigrees segregating Golden Retriever muscular dystrophy (GRMD), and to confirm the concordant segregation of the mutation in all carrier...
Topics
- Alleles
- Animals
- Base Sequence
- Creatine Kinase
- DNA
- DNA Primers
- Dog Diseases
- Dogs
- Exons
- Female
- Genetic Carrier Screening
- Genetic Linkage
- Genotype
- Male
- Molecular Sequence Data
- Muscular Dystrophy, Animal
