Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inactivation of the Very Strong HCMV Immediate Early Promoter by DNA CpG Methylation<i>In Vitro</i>

1 Jan 1996

Abstract excerpt

The influence of DNA methylation in vitro on the activity of the very strong human cytomegalovirus (HCMV) major immediate early (IE) modulator/enhancer/promoter region was investigated by transient transfection experiments of premonocytic HL-60 cells. While sequence-specific methylation of the major IE enhancer and/or modulator with the cytosine methyl-transferases FnuDII, HhaI and HaeIII had no significant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8722321
DOI: 10.1515/bchm3.1996.377.3.195

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inactivation of the Very Strong HCMV Immediate Early Promoter by DNA CpG Methylation<i>In Vitro</i>PMID 8722321Read ↗

Lytic infection of permissive cells with human cytomegalovirus is regulated by an intrinsic ‘pre-immediate-early’ repression of viral gene expression mediated by histone post-translational modificationSemantic proximity Read ↗

Dynamic histone H3 acetylation and methylation at human cytomegalovirus promoters during replication in fibroblasts.Semantic proximity Read ↗

A cis-acting element in the major immediate-early (IE) promoter of human cytomegalovirus is required for negative regulation by IE2Semantic proximity Read ↗

The control of human cytomegalovirus latent and lytic gene expression by chromatin remodellingSemantic proximity Read ↗

Establishment of Murine Cytomegalovirus Latency In Vivo Is Associated with Changes in Histone Modifications and Recruitment of Transcriptional Repressors to the Major Immediate-Early PromoterSemantic proximity Read ↗

Effect of a modulator deletion on transcription of the human cytomegalovirus major immediate-early genes in infected undifferentiated and differentiated cellsSemantic proximity Read ↗

Human cytomegalovirus ie2 negatively regulates alpha gene expression via a short target sequence near the transcription start siteSemantic proximity Read ↗

Repression by a differentiation-specific factor of the human cytomegalovirus enhancer.Semantic proximity Read ↗

Ets-2 repressor factor recruits histone deacetylase to silence human cytomegalovirus immediate-early gene expression in non-permissive cellsSemantic proximity Read ↗

Insertion of core <scp>CpG</scp> island element into human <scp>CMV</scp> promoter for enhancing recombinant protein expression stability in <scp>CHO</scp> cellsSemantic proximity Read ↗

The Effect of DNA Methylation on Gene Regulation of Human PapillomavirusesSemantic proximity Read ↗

A cis repression sequence adjacent to the transcription start site of the human cytomegalovirus US3 gene is required to down regulate gene expression at early and late times after infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.