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Article

Alteration of Na(+)-coupled transport in site-directed mutants of the melibiose carrier of Escherichia coli.

Biochimica et biophysica acta - 25 Jul 1996

Franco P J, Wilson T H

Abstract excerpt

Asn-58 of the Escherichia coli melibiose carrier was replaced by Ala, Leu, Ser, and Gln. Trp-54 was replaced by Leu and a double mutant Leu-54/Ala-58 was constructed using site-directed mutagenesis. Cation/sugar cotransport and sugar-induced cation uptake were studied for each mutant. The change of Asn-58 to Ala results in a nearly complete loss of Na(+)-stimulated galactoside transport as well as...

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Identifiers

PMID: 8703979
DOI: 10.1016/0005-2736(96)00062-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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