Article
Apolipoprotein E2 (Arg-136-->Cys), a variant of apolipoprotein E associated with late-onset dominance of type III hyperlipoproteinaemia.
European journal of clinical investigation - 1 Jan 1996
Feussner G, Albanese M, Mann W A, Valencia A, Schuster H
Abstract excerpt
Type III hyperlipoproteinaemia (HLP) is usually associated with homozygosity for apolipoprotein (apo) E2 (arg-158-->Cys). We identified a 46-year-old white female with severe hyperlipidaemia and the heterozygous apo E3/2* phenotype. Typical clinical characteristics of type III HLP, i.e. palmar xa...
Topics
- Adolescent
- Adult
- Age of Onset
- Aged
- Amino Acid Sequence
- Apolipoprotein E2
- Apolipoproteins E
- Arginine
- Base Sequence
- Cysteine
- Female
- Genetic Variation
- Heparin
- Humans
- Hyperlipoproteinemia Type III
- Isoelectric Focusing
- Lipoproteins
- Male