Genetic redundancy caused by gene duplications and its evolution in networks of transcriptional regulators.

Abstract excerpt

In various organisms loss-of-function mutations of individual genes with unexpectedly weak or no phenotypic effects in the homozygous state have been observed. In several of these case, independent evidence shows that the respective gene products do have essential biological functions. An explana...

Topics

• Computer Simulation
• Evolution, Molecular
• Gene Expression Regulation
• Gene Frequency
• Genes, Homeobox
• Models, Genetic
• Multigene Family
• Mutation
• Phenotype
• Transcription Factors
• Transcription, Genetic