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Article

Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D).

International immunology - 1 May 1996

Wagner S D, Elvin J G, Norris P, McGregor J M, Neuberger M S

Abstract excerpt

Antibody diversification by somatic hypermutation occurs by the introduction of nucleotide substitutions in and around the rearranged Ig V gene segments. Several characteristics of the process suggest that the introduction of mutations is linked to Ig gene transcription. Since there is a connection between mutation and repair with indications that both processes might show linkage to transcription, we asked...

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Identifiers

PMID: 8671657
DOI: 10.1093/intimm/8.5.701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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