Polymyalgia rheumatica is associated with both HLA-DRB1*0401 and DRB1*0404.

doi:10.1093/rheumatology/35.7.632

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Article

Polymyalgia rheumatica is associated with both HLA-DRB10401 and DRB10404.

British journal of rheumatology - 1 Jul 1996

Haworth S, Ridgeway J, Stewart I, Dyer P A, Pepper L, Ollier W

Abstract excerpt

The frequency of HLA-DRB1 alleles was determined in 68 Caucasoid patients with polymyalgia rheumatica (PMR) and 140 controls using polymerase chain reaction (PCR) sequence-specific oligonucleotide typing. In keeping with previous studies, an increased frequency of DRB1*04 was observed in patients [55.9% vs 35.0%, odds ratio (OR) 2.4, 95% confidence interval (CI) 1.3-4.4]. HLA-DRB1*0101 frequency was also...

Topics

Aged
Alleles
Autoantibodies
Disease Susceptibility
Epitopes
Female
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Male
Polymyalgia Rheumatica
Thyroid Gland

Source

Open in PubMed

Identifiers

PMID: 8670595
DOI: 10.1093/rheumatology/35.7.632

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