Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunogenetics of polymyalgia rheumatica.

British journal of rheumatology - 1 Oct 1990

Sakkas L I, Loqueman N, Panayi G S, Myles A B, Welsh K I

Abstract excerpt

Evidence suggests that polymyalgia rheumatica (PMR) may be an immune-mediated disease. Therefore, the role of HLA class II genes, the switch region of immunoglobin mu and alpha 1 heavy chain as the T-cell receptor (TcR) genes were investigated by Southern blot analysis. The frequency of DR4 specificity was increased in PMR (67.4% versus 30.3%; P = 0.00017). No association was found with the DQA and DQB genes, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Genes
Share to HLA-DQ Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-DR Antigens

Share to Immunogenetics

Share to Immunoglobulin mu-Chains

Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Antigen, T-Cell

Source

Identifiers

PMID: 1977488
DOI: 10.1093/rheumatology/29.5.331

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunogenetics of polymyalgia rheumatica.PMID 1977488Read ↗

Immunogenetics of polymyalgia rheumatica.Semantic proximity Read ↗

Polymyalgia rheumatica is associated with both HLA-DRB1*0401 and DRB1*0404.Semantic proximity Read ↗

Molecular analysis of HLA-DR polymorphism in polymyalgia rheumatica. Swiss Group for Research on HLA in Polymyalgia Rheumatica.Semantic proximity Read ↗

DRB1 alleles in polymyalgia rheumatica and rheumatoid arthritis in southern France.Semantic proximity Read ↗

Distribution of HLA-DRB1 alleles of patients with polymyalgia rheumatica and giant cell arteritis in a Mediterranean population.Semantic proximity Read ↗

Immune response factors in rheumatic heart disease: meta-analysis of HLA-DR associations and evaluation of additional class II alleles.Semantic proximity Read ↗

HLA-DRB1 alleles associated with polymyalgia rheumatica in northern Italy: correlation with disease severity.Semantic proximity Read ↗

HLA class II haplotypes associated with pulmonary interstitial lesions of polymyositis/dermatomyositis in Japanese patients.Semantic proximity Read ↗

HLA-DRB1 alleles in polymyalgia rheumatica, giant cell arteritis, and rheumatoid arthritis.Semantic proximity Read ↗

Rheumatic Fever and Rheumatic Heart Disease: Genetics and PathogenesisSemantic proximity Read ↗

Immunosusceptibility genes in rheumatoid arthritis.Semantic proximity Read ↗

Rheumatic fever: from innate to acquired immune response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.