Article
HLA-DRB1 allele distribution in polymyalgia rheumatica and giant cell arteritis: influence on clinical subgroups and prognosis.
Seminars in arthritis and rheumatism - 1 Aug 2004
Martínez-Taboda Víctor M, Bartolome M Jose, Lopez-Hoyos Marcos, Blanco Ricardo, Mata Cristina, Calvo Jaime, Corrales Alfonso, Rodriguez-Valverde Vicente
Abstract excerpt
OBJECTIVE: To evaluate HLA-DRB1 associations in patients with polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) in the Spanish population, especially those alleles that include the disease-linked sequence motif DRYF (positions 28 to 31 of the HVR2). METHODS: We performed a PCR based HLA-DRB1 genotyping in 89 PMR patients, 44 GCA patients, and 99 unrelated healthy controls from the same geographic area....
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