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Article

EBV induces proliferation of immature human thymocytes in an IL-2-mediated response.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 1996

Todd S C, Tsoukas C D

Abstract excerpt

The receptor for EBV, CD21 is expressed on a population of immature human thymocytes and facilitates infection of these cells by EBV. Thymocytes infected by EBV become responsive to exogenous rIL-2- or CD2-mediated stimulation in vitro. To address whether such costimulation may be provided by thymic presenting cells and to study the cellular effects of EBV infection, the present work utilizes thymocyte cultures...

Topics

Antibodies, Blocking
Cell Aggregation
Cell Division
Child
Herpesvirus 4, Human
Humans
In Vitro Techniques
Interleukin-2
Kinetics
Lymphocyte Activation
Phenotype
Receptors, Antigen, T-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Complement 3d

Receptors, Interleukin-2

T-Lymphocyte Subsets

T-Lymphocytes

Viral Matrix Proteins

Source

Identifiers

PMID: 8666790

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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