Article
Cellular deformation reversibly depresses RT-PCR detectable levels of bone-related mRNA.
Journal of biomechanics - 1 Dec 1995
Stanford C M, Stevens J W, Brand R A
Abstract excerpt
Osteoblastic cells respond to mechanical stimuli with alterations in proliferation and/or phenotypic expression. In some cases, these responses occur within only a few applications of stimuli (i.e. 'cycle-dependent trigger response') rather than in a dose-dependent manner. To explore potential mechanisms of the cycle dependent trigger response, we raised the following questions: (1) Does strain of bone cells...
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