Article
High-affinity IgE receptor (FcepsilonRI)-bearing cells in bronchial biopsies from atopic and nonatopic asthma.
American journal of respiratory and critical care medicine - 1 Jun 1996
Humbert M, Grant J A, Taborda-Barata L, Durham S R, Pfister R, Menz G, Barkans J, Ying S, Kay A B
Abstract excerpt
Asthma is characterized by bronchial mucosal inflammation. Although allergen-induced activation of cells binding allergen-specific immunoglobulin E (IgE) through high-affinity receptors (Fc(epsilon)RI) is believed to play some role in asthma, inappropriate synthesis of total or allergen-specific IgE cannot be demonstrated in some ("intrinsic") patients despite the fact that the nature of the bronchial...
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