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Article

Cloning and Functional Expression of mCCR2, a Murine Receptor for the C-C Chemokines JE and FIC

1 May 1996

Abstract excerpt

The C-C chemokines human monocyte chemoattractant protein-1 and -3 (MCP-1 and MCP-3) and mouse JE and FIC are potent activators of monocytes. Several receptors for MCP-1 and MCP-3 have been cloned from human monocytic cell lines, and one of these receptors, CCR2B, binds both MCP-l and MCP-3. Thus far, no murine receptors for JE or FIC have been reported. We have cloned a novel murine C-C chemokine receptor,...

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PMID: 8662823
DOI: 10.1074/jbc.271.20.11603

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