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Measles virus infection of thymic epithelium in the SCID-hu mouse leads to thymocyte apoptosis

1 Jun 1996

Abstract excerpt

Mortality from measles is caused mostly by secondary infections associated with the depression of cellular immunity. The mechanism of immune suppression and the role of virus strain differences on the immune system are incompletely understood. SCID-hu mice were used to determine the effects of virulent, wild-type (Chicago-1) and avirulent, vaccine (Moraten) strains of measles virus (MV) on the human thymus in...

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PMID: 8648708
DOI: 10.1128/jvi.70.6.3734-3740.1996

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