Article
P-glycoprotein expression in canine lymphoma: a relevant, intermediate model of multidrug resistance.
Cancer - 1 May 1996
Lee J J, Hughes C S, Fine R L, Page R L
Abstract excerpt
BACKGROUND: Despite extensive investigation, the role of MDR of human cancer remains unclear. Canine lymphoma is a spontaneously arising correlate of human non-Hodgkin's lymphoma that may complement other in vivo models for investigation of issues related to MDR. METHODS: Immunoreactivity of primary antibodies to the human MDR1 gene product, p-glycoprotein 170 (Pgp), were determined in both a retrospective (n=76)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
