Article
Spontaneous canine mammary tumors. A model for monoclonal antibody diagnosis and treatment of human breast cancer.
Laboratory investigation; a journal of technical methods and pathology - 1 Aug 1994
Mottolese M, Morelli L, Agrimi U, Benevolo M, Sciarretta F, Antonucci G, Natali P G
Abstract excerpt
BACKGROUND: The increasing availability of monoclonal antibodies to human breast tumor-associated antigens offers a new means to evaluate whether antigenic similarities exist between human and animal breast tumors. The study of the biology of spontaneous mammary tumors in the dog, one of the most frequent neoplasias in this domestic animal, may be of interest in providing an experimental model for the clinical...
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