Article
The paralysé mouse mutant: a new animal model of anterior horn motor neuron degeneration.
Journal of neuropathology and experimental neurology - 1 Jun 1996
Houenou L J, Blondet B, Li L, Murawsky M, Oppenheim R W, Rieger F
Abstract excerpt
The survival and morphometric characteristics of lumbar spinal motoneurons were examined in the paralysé mouse mutant. Affected (par/par) mice can be first recognized at approximately postnatal day (PN) 7 to 8 and are characterized by their smaller-than-normal body size, a progressive generalized muscle weakness, and lack of coordination. Mutant mice die by PN16-18, when they have become almost completely...
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